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Understanding PESA, MESA, TESA and TESE

Understanding PESA, MESA, TESA and TESE

A plain-language introduction to sperm retrieval.

Illustrative patient information image
Male fertility

Different techniques, a specific purpose

PESA and MESA access sperm in the epididymis, using needle aspiration or a microsurgical approach. TESA and TESE access the testis, using aspiration or tissue extraction. The technique is selected for a specific clinical situation.

Part of a wider fertility plan

Retrieval may be considered when sperm cannot be obtained in the ejaculate. A reproductive team explains how it fits with assisted reproduction and whether other assessment is needed.

Questions to take to your consultation

Ask why retrieval is being considered, the alternatives, anaesthesia, recovery and how retrieved sperm would be used or stored. Finding sperm and achieving pregnancy are separate outcomes; neither is guaranteed.

This information is intended for general education and does not replace individual medical evaluation. A procedure described here may not be suitable for every patient.

You don’t have to keep guessing what the symptom means.

Whether the concern is painful, persistent or difficult to talk about, start with a conversation about what is happening and what to do next.

How can we help?